CBD Gummies For Essential Tremor

CBDISTILLERY

Buy CBD Oil Online

Find out if CBD oil could be the solution to managing your essential tremor. We cover the current research and provide tips on buying the best products. When it comes to tremor diseases like essential tremor and Parkinson's, natural remedies' effects vary from one to another. Find what suits you at Steadiwear! Trial of Cannabis for Essential Tremor This is a pilot trial to evaluate the safety and efficacy of a combined oral formulation of THC and CBD in patients with Essential Tremor.

Essential Tremor & CBD Oil: A Landmark Clinical Trial & Buying Tips

Cannabidiol (CBD) oil is well known for helping people with conditions that feature tremors as one of their symptoms, such as Parkinson’s disease. But there is one condition that has been largely overlooked—until now.

It may not be a life-threatening condition, but essential tremor (ET) affects a large proportion of the population. The exact number of sufferers is difficult to pinpoint, but reports estimate 2.2%–3% of Americans have ET, making it at least eight times more prevalent than Parkinson’s.

What Is Essential Tremor?

Essential tremor is characterized by involuntary shaking of body parts, but is not associated with Parkinson’s disease. Most often ET will manifest as shaking of the hands when performing manual tasks, such as tying your shoes or drinking from a glass. Essential tremor can also affect the head, voice, and legs.

One of the issues with finding an effective treatment for ET is that its origins are not well understood. There is thought to be an element of genetic predisposition, with 50% of essential tremor sufferers having inherited it from a parent. However, where the hereditary trait lies within the genes, and how it manifests itself is still a mystery.

There is no specific test which can be used to diagnose essential tremor, so a diagnosis is based on a review of the reported symptoms which can often be confused for Parkinson’s disease. Because of this, there is no cure, nor any preventative treatment available for ET, leading many to self-treat with more natural products like CBD oil.

How CBD Oil Can Help Essential Tremor

At this point in time, all that is currently known about CBD oil and ET is based on anecdotal evidence. Some people report having improved symptoms when using cannabis or CBD oil, with the frequency and intensity of their tremors noticeably reduced.

This prompted a team at the University of California, San Diego (UCSD) to undertake a targeted study on the use of CBD oil to help ET. The trial took place in 2019 and aimed to understand whether cannabinoids such as CBD can be used in a medical setting to provide relief to people who suffer from essential tremor.

Based on other research that has been conducted on similar conditions, CBD may possess the therapeutic properties that ET patients seek.

CBD Oil for Muscle Spasticity

The effects that CBD oil has on reducing muscle spasticity have been widely reported and accepted. Recently, CBD oil was approved as a medical treatment for spasms related to multiple sclerosis (MS) under the brand name Sativex in places like the U.K. and Canada.

Muscles contract when chemical messengers are sent to muscle tissue by the central nervous system. If an excess amount of these messengers are released and flood the muscle tissue, the area is forced to continuously contract, leading to twitching, tremors, and tightness. CBD oil has been shown to restrain the release of these messengers, allowing the muscles to relax.

CBD Oil as a Muscle Relaxant

While at first glance it may seem like the link between CBD oil’s relaxing effects and ET is a tenuous one, the biological properties of CBD suggest a significant potential for benefit. In addition to reducing spasticity, an additional way that CBD oil can relax muscles is through its reduction of anxiety and promotion of general relaxation. CBD oil is able to reduce levels of the stress hormone cortisol and induces higher levels of the feel-good hormone dopamine.

Not only can CBD help your muscles relax from a neurological point of view, but the cannabis plant also contains two anti-inflammatory substances that have been shown to act as muscle relaxants: Delta-limonene and Beta-myrcene.

With this evidence in mind, the likelihood that CBD oil can help those who suffer from ET looks positive. This then begs the question, why hasn’t CBD and ET research been conducted sooner?

The Barriers to CBD Testing

The red tape surrounding the use of CBD in clinical research has long been an issue for scientists across the U.S., with the clinical trial at UCSD being no exception. Despite many states, including California, having relaxed laws on the use of cannabis for medical and recreational purposes, federal law takes a much harsher stance.

The U.S. Drug Enforcement Agency (DEA) considers any derivative of cannabis to be an illegal substance and requires universities and research facilities to obtain cannabis products through the National Institute on Drug Abuse (NIDA). And getting materials from the NIDA is a notoriously slow process.

To complicate the matter further, the researchers on the UCSD study wanted to use CBD capsules, which aren’t available through the NIDA. In order for the trial to have been given the green light, permissions had to be sought to import CBD capsules from Canada, where medical marijuana is federally legal.

How to Use CBD oil for Essential Tremor

While the results from the trial at UCSD aren’t available yet, if you are struggling to carry out daily tasks due to ET, CBD oil may be an option worth exploring based on its beneficial biological properties.

There are two main cannabinoids found in cannabis: CBD and THC. Both work differently within the body’s endocannabinoid system to yield different health benefits and ideally, you’d take both by way of a full-spectrum product. A full-spectrum CBD oil is also more likely to contain limonene and myrcene, allowing you to experience the muscle relaxing properties of all the hemp plant’s natural compounds at an amplified level, thanks to the entourage effect. The entourage effect refers to the fact that substances in the whole hemp plant produce stronger effects when they are present together than they do on their own.

But, before buying a CBD oil product that contains THC, make sure you understand whether or not it is legal for you to do so. A full-spectrum CBD product with a higher THC content is only going to be available to people who live in a state with access to medical or recreational cannabis products. Everywhere else, CBD oil will fall under the federal guidelines, and must have a THC content that is 0.3% or less. If you live in a state where it’s illegal to consume THC, or you’d simply prefer not to consume it, look for a broad-spectrum CBD product. Broad-spectrum CBD oils contain all of the cannabinoids and terpenes of a full-spectrum product except for THC.

CBD Delivery Formats

There are lots of different CBD oil delivery formats available. Most people will choose a product based on their unique needs.

For many people with ET, a supplement routine that includes daily doses of CBD oil tinctures, capsules, or edibles is likely to be most effective. This will ensure that CBD is always in the system and working to create equilibrium over longer periods of time.

CBD capsules and edibles will provide the longest lasting relief, typically 4 to 6 hours, but will also take the longest to take effect. Due to the fact that they have to pass through the digestive system, it could take up to an hour for you to feel the benefits of a CBD edible or capsule.

For the sudden onset of tremors, an inhalant, like a CBD vape or CBD flower may be best. In these formats, the CBD is absorbed through the lungs, showing effects in a matter of minutes. When struck with debilitating tremors, time is of the essence. The only drawbacks of using an inhaled CBD product is that the effects are typically gone within an hour, and it is not always appropriate or convenient to vape or smoke.

See also  CBD Oil Infused Pillow

CBD oil drops or tinctures may provide the best, most balanced solution. This format can easily be used as a daily supplement and the bottles are portable and discreet enough to be used for the sudden onset of symptoms. The effects do not appear as quickly as with CBD vapes or flower, but they typically occur within a half hour and can last anywhere from 2 to 4 hours. This format also makes it easy to control dosage and take more or less CBD oil as required. It is worth noting, however, that if tremors are severe enough, tinctures and drops may be complicated to administer on your own.

For more detailed information on delivery formats, check out our beginner’s guide here.

CBD Oil Dosage for Essential Tremor

Before you start taking CBD oil for ET, it is important to talk to your doctor. While CBD oil has very few side effects and is generally safe for use, it can interact with some common medications, so it is best to make sure that you are able to use CBD oil safely and effectively.

Unfortunately, there is no single dose that will work for essential tremor. What works for one person may not work for another. Start slowly with the lowest recommended dose listed on your CBD product. Once you get an idea of how you respond to CBD oil, you can adjust the dosage from there.

If you’re looking for a quick point of reference, at CBD Oil Review, we have analyzed hundreds of products and have come up with the following:

The CBD Oil Review Serving Standard is 25 mg of CBD, taken twice daily.

If this amount does not produce the results you were looking for, increase the dose by 25 mg every 3 to 4 weeks until the desired effects are achieved.

You can find detailed CBD dosage information and tips here, or speak to a naturopathic doctor for the most personalized CBD dosage advice.

The Best CBD Oil for Essential Tremor

If you are afflicted with ET and want to try treating it with CBD oil, there are a variety of products available that can be purchased easily, and legally, in most states. The best CBD oil to use for ET is one which is high quality and rigorously tested.

For that reason, it is recommended that you choose a brand which uses organically grown, sustainably sourced hemp to ensure that your CBD oil is free of harmful pesticides, fertilizers, and herbicides. Also, look for those that have a readily accessible Certificate of Analysis (COA), which will indicate that the products have been tested for heavy metals and other contaminants. A COA is most reliable if it has been produced by a third-party laboratory, as this removes any likelihood of bias in the results.

Learn more about how to choose the best CBD oil for you with these 7 tips for buying CBD oil.

If you are unhappy with the management of your ET, or feel that your daily life is becoming restricted by it, CBD oil may provide an alternative and effective treatment option.

Sources:

  1. Elan D. Louis et al. (2014) How Many People in the USA Have Essential Tremor? Deriving a Population Estimate Based on Epidemiological Data – National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137360/
  2. (2019) Trial of Cannabis for Essential Tremor – ClinicalTrails.gov https://clinicaltrials.gov/ct2/show/NCT03805750
  3. PabloPandolfo et al. (2011) Cannabinoids inhibit the synaptic uptake of adenosine and dopamine in the rat and mouse striatum – Elsevier B.V. https://www.sciencedirect.com/science/article/abs/pii/S0014299911000537
  4. Eric P. Baron et al. (2018) Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort – National Center for Biotechnology Information https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968020/
  5. T Gurgel do Vale et al. Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) n.e. Brown – National Library of Medicine https://pubmed.ncbi.nlm.nih.gov/12587690/

Health Conditions

CBD Oil & Chronic Pain: Does it Really Work?

Perhaps you’ve heard of people using CBD oil for chronic pain and, like most people, you wonder if it is .
Learn More

CBD for Colitis: Can Colitis Symptoms Be Managed with CBD?

Suffering from colitis is nobody’s idea of a walk in the park. Most people with colitis suffer with it for .
Learn More

Crohn’s Disease and CBD Oil: Current Research and Benefits

For an estimated 780,000 people in the U.S., Crohn’s disease is a daily reality, impacting sufferers’ ability to live a .
Learn More

Gut Health and CBD Oil: A Complete Guide

At some point during your education, you were taught that your heart pumps blood, your lungs circulate oxygen, and your .
Learn More

Liver Disease & CBD Oil: Risks, Benefits, & Research

The seriousness and prevalence of liver disease, particularly in the western world, is real, and underrepresented. It is difficult to .
Learn More

ALS & CBD Oil: Promising Research on Cannabinoids & Buying Tips

Amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s Disease, is a neurodegenerative disease with no known cause and .
Learn More

Neurodegeneration & CBD Oil: Can It Rebuild & Reverse the Damage?

Neurodegenerative diseases like Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease are terrifying and relatively common conditions. While more research is .
Learn More

Kidney Disease & CBD Oil: Research on Symptoms & Possible Benefits

Kidney disease is a common but complicated illness. According to the National Kidney Foundation, nearly 37 million Americans have kidney .
Learn More

Metabolic Syndrome & CBD Oil: Addressing Multiple Conditions

Metabolic syndrome covers a range of health conditions that all pose cardiovascular complications, that are all interlinked, and that together .
Learn More

6 Smart Questions to Ask BEFORE You Buy CBD

Get the Ultimate CBD Buyer’s Guide and you won’t look at CBD the same way again!

A Complete Guide to Natural Remedies for Hand Tremors – CBD Oils Versus Gloves & Utensils

Cannabinoids such as Cannabidiol (CBS) have been looked at for its ability to relax muscles, ease seizures, and provide relief for tremor-like symptoms (1). It has been shown that cannabinoids found in the marijuana plant interact with the body’s endocannabinoid system (ECS). This system is in charge of body functions and regulating controls. It has been suggested that CBS can play a role in combination with the ECS to target cannabinoid receptors in the brain and body that control our muscles (1).

What Is the Endocannabinoid System (ECS)?

The Endocannabinoid system (ECS) is a cell signaling system within the human body that involves 3 components; endocannabinoids, receptors, and enzymes. (2)

  • Cannabinoid receptors act as information antennas, letting the body know on a biochemical level how the inner cell environment is. A good example of its abilities is the interaction with tetrahydrocannabinol (THC), which tells the brain to give the user a high feeling (3).
  • Endocannabinoids are molecules produced within the body, similar to cannabinoids. The endocannabinoids help the body to remain in homeostasis or a healthy state (3).
  • Enzymes on the other hand help to regulate the body, they break down endocannabinoids once they are used so that they don’t continue to affect the body (3).

This system was discovered while exploring the effects of THC, a cannabinoid found in cannabis (marijuana). Regardless of whether one uses cannabis or not, the ECS is active and plays a role in functions and processes within the body such as, sleep, mood, appetite, memory, pain, reproduction and fertility (2). It is activated when the body is stressed, strained, or injured. The ECS then releases endocannabinoids that help to bring the body back to its base resting state where it is balanced again (2).

What are CBD Oils?

Cannabidiol (CBD) is the second most prevalent active ingredient of cannabis (marijuana). While CBD is an essential component of marijuana, it is derived directly from the hemp plant, which is a cousin of the marijuana plant. The hemp plant has two major components; the Cannabidiol (CBD) and Tetrahydrocannabinol (THC), CBD is extracted and made into an oil with very low concentrations of THC therefore exerting no psychotropic effects (4). CBD however, does have a number of non-mood-altering effects including fatigue, nausea, irritability, and it can also increase the amount of blood thinner in your blood. (5) THC is known to relax, enhance sensory activity, reduced aggression, and most often lead to a sense of fatigue and hunger, CBD on the other hand is proposed to have many therapeutic properties with low risks (3). CBD studies have connected its ability to alleviating symptoms and side effects for chemotherapy, multiple sclerosis (MS), epilepsy, calming anxiety, glaucoma, controlling tremors associated with Parkinson’s Disease (PD), brain and spinal injuries, and contains anti-inflammatory properties (3). Essential tremor is another condition that is being tied to CBD use however, its application has not been proven to be effective just yet, it is under research (6). It is notable that the Food and Drug Administration (FDA) has acknowledged CBD’s medicinal benefits (1). The epilepsy drug Epidiolex is the first-ever CBD-based drug the organization has approved (1).

See also  Ancient Life CBD Oil

Characteristics of Essential Tremor & Parkinson’s Disease

Essential tremor (ET) is a disorder of the nervous system that is characterized by involuntary and rhythmic shaking within the body. Most commonly, it occurs in the hands making simple takes such as eating and drinking difficult (1). However, it is known to also affect the arms, head, face and larynx. These tremors can start at a mild range and grow to become severe overtime (6).

Parkinson’s Disease (PD) is a long-term disorder of the central nervous system and is characterized by stiffness, trembling of limbs, imbalances of the limbs, and loss of muscle control (7). The typical Parkinson’s Disease tremor is known to show itself when at rest, and subsides when the body part is in use or active (8). For example, your hand may shake when sitting, however, when you go to shake another individual’s hand, the hand tremor becomes less severe or disappears (8). The tremors can occur in the hand, lower lip, jaw, or legs and can interfere with daily activities such as dressing, walking and other fine motor skills (8). These tremors have a slow progression and are less common among younger people with PD (8).

The biggest difference between PD tremors and other tremors is that PD tremors are resting tremors versus other conditions are characterized by active tremors; tremors that lessen at rest and increase when one is doing something (8).

How Can CBD Play A Role in Your Hand Tremor Management?

When using CBD oil for hand tremors the CBD in the oil can target and regulate the ESC receptors which are responsible for muscle movement (6). These receptors are located in the brain and body. The regulation of these receptors allows CBD oil to relax, reduce inflammation, and ease symptoms of tremors (6). There have been studies that confirm these interactions and confirm that CBD can effectively act as a neuroprotectant (6).

In a study conducted by Dr. Handforth, CBD is tested in a variety of doses and it is noted that robust suppression of tremor in mice is possible, without showing any signs of impairment or sedation (9). The research team also went on to discover what receptors in the brain may be involved in the noted effects. It was suggesting that CBD activates the 5HT1a receptors to suppress tremor by activating the TRPV1 receptor (9).

Individuals affected by hand tremors find it difficult to complete hand-related tasks because of the consistent shaking. A recent discovery for CBD use is its potential in treating hand tremors. People with shaky hands have started making use of the CBD’s anti-tremor mechanisms, many of which have found that daily doses of CBD products are successful in managing their symptoms (10). Many of the prescription drugs used to treat essential tremors can sometimes affect mood or cause depression (10). CBD is an alternative natural remedy with anti-tremor capabilities that has a good safety profile, along with minimal side effects (10).

In order to have the best experience when using CBD, it is crucial that one does their research on which brands are trustworthy and best fit your condition. CBD is offered by a variety of brands which differ in application methods such as oils, balms, creams, edibles and vape (10). Furthermore, it is very important that you read the product labels and descriptions thoroughly to make sure that contents are present, active and not altered in any way (11). You should be aware of products with high amounts of THC or products that don’t actually contain CBD (10). Please keep in mind that CBD generally is known to have few side effects, it is still recommended that one should consult a neurologist or physician who knows your medical history before using it. The doctor may be able to assist with the correct dosage according to the method of administration for your condition while making sure that it does not have a negative effect on the pre-existing medication you are taking, if any (10).

Using CBD For Hand Tremors (Dosage and Use)

The two most popular ways of taking CBD for hand tremors is using a CBD oil or vaping the CBD. Everyone reacts differently to CBD so it is crucial to experiment with the method and amount used to see what works best to relieve your particular hand tremor condition (6). It is suggested that one should start with a low dosage such as 1 drop, 3 times a day and increase it according to your tolerance and how much relief it provides (6). On an average, about 25mg is a good amount for someone with non-severe symptoms (6). It is important to note that depending on the product, the CBD content should be used with caution as no single ratio is right universally. CBD comes in 2 forms that work for hand tremors; CBD oil, which comes in a bottle with a dropper. A drop or two is placed under the tongue to allow the oil to absorb into the body. It also can be used as a Vaping CBD, these are E-Liquids available to incorporate into the vape pen. This allows for a quicker pathway into the body and hence the fastest way to experience the effects. The vapor enters the lungs first and reaches the bloodstream immediately.

Learn more about the Steadi-Two- a revolutionary glove designed to reduce hand tremors.

Which CBD Oil Is Right for You?

There are many CBD oils on the market however, it is very important to differentiate that not all of them are made equally. There are no CBD products currently approved by the FDA, and nor are all of them equally as effective (12). When deciding to use CBD products be aware of any negative and positive reactions. If your on the market to purchase CBD oils here are some tips to keep in mind while exploring all the options available:

Tips for When Shopping for CBD Oil

    1. Look for products that have been made by a state that have legalized recreational/ medical use of cannabis (13) and for products derived from high-resin cannabis grown sustainably in accordance with Regenerative Organic Certification (ROC) standards (13). Keep in mind that locally grown products will most likely be more expensive than imported products (14).
    2. Look for full spectrum CBD oil extracts that contain less than 0.3% of THC (12). Full spectrum represents numerous cannabis compounds, it does not isolate only the CBD. If you choose to not have THC in your CBD oil you can look for broad spectrum CBD oil products that include other cannabis components except for THC (13)
    3. Reach out to the brands directly if you have questions, do not shy away. If you do not get a response look for another brand that will provide answers.
    4. Look at the product labels to see if it indicates the amount of CBD and THC per dollar (13).
    5. Look out for CBD vape cartridge products with harmful ingredients such as thinning agents; propylene glycol and polyethylene glycol (13).
    6. Beware of claims of CBD being derived from the seed or stalk of the hemp plant. CBD is not found in hemp seed and very little can be extracted from the stalk (13).
    7. Look for products that were tested by a third-party laboratory (13) . Certificates for analysis from these third-party laboratories require paid tests and are important in determining the CBD quality (14).
    8. Make sure it is meant to be taken orally (12).
    9. Look on the product to make sure it indicates a manufacturing date and a batch number (13)

    Top 10 CBD Oils

    If you want to take a dive into CBD oils, here is a list of 6 featured on Huffpost’s list of best CBD products (15). The following brands offer more than just CBD oils however for the purpose of this blog topic surrounding Hand tremors we will be looking specifically at brands that offer CBD products in Oil form.

    CBD Oils Versus Gloves & Utensils for Hand Tremors

    CBD oils are used within the body to help a variety of conditions and symptoms. Currently, on the market they are a fairly new product and require a lot more investigation and research to recommend as a management tactic for ET and PD Hand tremors (14). Some research shows that CBD can play a role in tremor management however, it is not supported by a governed body just yet for hand tremors specifically due to ET. As a result of the uncertainty of CBD’s effects it might be worth checking out other alternative solutions before diving into products that may have side effects on the body in the short and long-term.

    It might be worth checking out assistive devices that are used externally on the body part that is tremoring to help improve daily activities. On the market currently there are a large variation of assistive devices available that cater to specific tasks such as, the Liftware steady spoon that helps to improve daily eating, and then there are some that aid in a vast number of activities such as, the Steadi-Two glove that is designed to help perform multiple tasks that one may struggle with throughout the day.

    The following table weighs out the positive and negative aspects of each type of product and our suggested rating for each product type that is available and you should further look into.

    • no psychotropic effects
    • Suggested to help to relief hand tremor possibly
    • proposed to help with hand tremor management
    • used for MS, PD, Epilepsy, injuries, and muscle pain
    • Does not work for everyone
    • Can test Positive for marijuana on a drug test as it may have traces of THC
    • Side effects such as, dizziness, fatigue, dry mouth, nausea, irritability, increase amount of blood thinners in blood
    • Effectiveness for hand tremors as a result of ET is still in the research phase
    • Must repurchase periodically
    • On-going cost ($$$)
    • Non-invasive
    • Works to counteract multiple challenges when dealing with hand tremors
    • One -time purchase
    • Instant tremor relief
    • Does not work for everyone, most cater to hand tremors from PD and ET
    • Price ($$ can vary depending on the brand)
    • Non-invasive
    • One-time purchase
    • Assists with eating
    • Does not work for everyone, sometimes griping is an issue
    • Works to counteract single eating activities
    • Price ($$ can vary depending on the brand)

    Placement of products within this blog in no way constitutes an endorsement, express or implied, of any product, service, or company by Steadiwear. This is strictly for awareness purposes.

    Interested in more information like this? Sign up for Steadiwear’s newsletter here ( https://steadiwear.com/?contact%5Btags%5D=newsletter&form_type=customer#ContactFooter ) to learn more and stay informed about your hand tremor.

    Featured Image: https://unsplash.com/photos/Ld9FQlMez8g

    (1) WayOfLeaf (2020). What’s Essential Tremor, and Can CBD Oil Help? Retrieved June 7 th , 2020, from https://wayofleaf.com/cbd/ailments/what-is-essential-tremor#:~:text=In%20the%20case%20of%20tremors,has%20become%20a%20patented%20neuroprotectant.

    (2) Rayple, C. (2019). A Simple Guide to the Endocannabinoid System. Retrieved June 7 th , 2020, from https://www.healthline.com/health/endocannabinoid-system

    ( 3) Neuravive. (2018). Essential Tremor and Cannabinoids. Retrieved June 7 th , 2020, from https://essentialtremortreatment.com/essential-tremor-cannabinoids/

    (4) Holland, K. (2019). CBD vs. THC: What’s the Difference? Retrieved June 7 th , 2020, from https://www.healthline.com/health/cbd-vs-thc

    (5) CBDOILreview. (2018). Blood Thinners and CBD Oil Interaction. Retrieved June 8 th , 2020, from https://cbdoilreview.org/diseases-conditions/cbd-oil-blood-thinners-interaction/

    (6) Bal, A. (2019). CBD for Essential Tremor. Retrieved June 8 th , 2020, from https://hemppedia.org/cbd-for-essential-tremor/

    (7) Bal, A. (2018). CBD for Parkinson’s Disease. Retrieved June 8 th , 2020, from https://hemppedia.org/cbd-for-parkinsons-disease/

    (8) Parkinson’s Foundation. (2020). Tremor. Retrieved June 8 th 2020, from https://www.parkinson.org/Understanding-Parkinsons/Symptoms/Movement-Symptoms/Tremor

    (9) IETF. (2015). ESSENTIAL TREMOR RESEARCH PROGRAM: CANNABIDIOL ANTI-TREMOR ACTION AND MECHANISMS. Retrieved June 8 th , 2020, from https://essentialtremor.org/resource/adrian-handforth/

    (10) Wheless, H. (2020). CBD for Essential Tremor: How It Can Help You Manage Your Symptoms. Retrieved June 8 th , 2020, from https://www.remedyreview.com/health/cbd-for-essential-tremors/

    (11) Grinspoon, P. (2020). Cannabidiol (CBD) – What We Know and What We Don’t. Retrieved June 8 th , 2020, from https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476

    (12) Cronkleton, E. (2020). Choosing a CBD Oil: 10 Favorite Oils to Try. Retrieved June 9 th , 2020, from https://www.healthline.com/health/best-cbd-oil

    (13) Project CBD (2019). How Do I Choose A CBD Product? Retrieved June 9 th , 2020, from https://www.projectcbd.org/how-to/10-tips-for-buying-cbd

    (14) Fendler, R. (2020). The 2020 Definitive Guide to Everything You Need to Know About CBD Oil. Retrieved June 9 th , 2020, from https://snacknation.com/blog/cbd-oil/#where-to-buy-cbd-oil

    (15) Nims, B. (2019). The Best CBD Products of 2019 That Are the Real Deal. Retrieved June 9 th , 2020, from https://www.huffingtonpost.ca/entry/the-best-cbd-products-of-2019-that-are-the-real-deal_l_5c4b745ce4b0287e5b8a87e0

    (16) Charlotte’s Web Stanley Brothers. (2020). Shop CBD; CBD Oils. Retrieved June 9 th , 2020, from https://www.charlottesweb.com/catalog/category/view/id/166?cat=141

    (17) Medterra. (2020). CBD Products. Retrieved June 9 th , 2020, from https://medterracbd.com/products

    (18) Made by Hemp. (2020). Find the Best CBD Oils for You. Retrieved June 9 th , 2020, from https://madebyhemp.com/

    (19) Endoca. (2020). Say Yes! To Clean CBD & Vitamins. Retrieved June 9 th , 2020, from https://www.endoca.com/

    (20) Lord Jones. (2020). Lord Jones Royal Oil. Retrieved June 9 th , 2020, from https://lordjones.com/products/lord-jones-royal-oil-1000-mg-cbd

    (21) CBDfx. (2020). All CBD Products: Buy Online. Retrieved June 9 th , 2020, from https://cbdfx.com/collections/products/#shop-now

    (22) Liftware. (2020). Liftware-Eat with Confidence. Retrieved June 9 th , 2020, from https://www.liftware.com/

    (23) Steadiwear. (2020). Steadi-One. Retrieved June 9 th , 2020, from https://www.steadiwear.com/

    Learn more about the Steadi-Two- a revolutionary glove designed to reduce hand tremors.

    Trial of Cannabis for Essential Tremor

    This is a pilot trial to evaluate the safety and efficacy of a combined oral formulation of THC and CBD in patients with Essential Tremor.

    Condition or disease Intervention/treatment Phase
    Essential Tremor Drug: CBD/THC Drug: Placebo oral capsule Phase 1 Phase 2

    Essential tremor (ET) is the most common neurological movement disorder, affecting up to 1% of the population and up to 5% of individuals over the age of 65. ET is characterized by often disabling tremors that occur when an individual moves. The tremors most commonly affect the hands, head, voice, and legs in order of frequency, leading to impairment in activities of daily living and morbidity. No pharmacological agent has been developed for ET, though existing agents such as propranolol and primidone are used off-label to reduce tremor amplitude. Deep brain stimulation surgery is often reserved for only individuals with the most severe tremors. Patients with ET have long reported tremor benefits with the use of cannabis, though no controlled trials have been conducted. The investigators plan to conduct the first double-blind, placebo-control clinical trial of cannabis in an oral capsule. Various validated tremor rating methods will be used to quantify tremor severity, while looking at tolerability and safety.

    How useful was this post?

    Click on a star to rate it!

    Average rating 4 / 5. Vote count: 1

    No votes so far! Be the first to rate this post.